【SCI专栏】回复审稿人，大战三百回合！
点击上面蓝字↑↑↑关注【解螺旋】
——日读一帖，解螺旋大V团队伴你科研路
作者：解螺旋.翠花
解螺旋出品，转载须经授权
SCI投稿是一段忐忑的路，上一篇我们曝光了两个不靠谱的SCI杂志，大家就赶紧绕道行走吧（查看上期文章，请在解螺旋公众号中回复379）。
今天我们来谈谈回复审稿人意见的几个要点。收到的审稿意见，少则几条，多则几十条， 面对这张战书，需要淡定，淡定，再淡定。首先分一分类，哪些需要细节修改，哪些需要补充实验，哪些需要好好查查文献战胜审稿人的刁难。想好了，再开始一场不见血光的战斗！
回合1：先礼后兵，礼貌开头
Thank you for your letter and for the reviewers’ comments concerning our manuscript entitled “文章题目”. These comments are all valuable and very helpful for revising and improving our paper, as well as the important guiding significance to our researches. We have studied comments carefully and have made corrections which we hope meet with approval. （你的提议太有用了，我论文的质量蹭蹭蹭就上去了！我们相当仔细研究了你的建议之类的话）The responds to the reviewer’s comments are as follows: .......
回合2：细节修改，不容小觑，一一作答，有礼有节
比如审稿人提出：图中需要补充比例尺
回复：As for the referee’s concern, we have added scale bars to the Figures.
比如审稿人提出：部分图片没有显著性差异
回复：As for the referee’s concern, we have indicated a significant difference with asterisk in figures.
比如审稿人提出：通篇语言问题不过关
回复：We are very sorry for the mistakes in this manuscript and inconvenience they caused in your reading. The manuscript has been thoroughly revised and edited by a native speaker, so we hope it can meet the journal’s standard. Thanks so much for your useful comments.
比如审稿人提出：补充缩写词的全称
回复：As for the referee’s concern, the full descriptions of the abbreviations like IHC, MTT etc have been supplemented in the revised manuscript.
比如审稿人提出：裂解液成分有问题
回复：We are very sorry for the mistake. Lentivirus-transduced cells were washed twice with PBS, and suspended in a lysis buffer (2% mercaptoethanol, 20% glycerol, and 4% SDS, in 100 mM Tris-HCl buffer, pH 6.8). The information for the lysis buffer has been corrected in the materials and methods.
回合3：补充实验，耗时耗力，如果不补，只能argue
比如审稿人提出：补充正常皮肤细胞作对照
Tips：如果你真的不想补，或者正常细胞株，你也买不到，还是查一查正常细胞株的名字，告诉审稿人你确实是去努力过，只是事与愿违啊！
回复：Indeed, it will be more convincing if we get a comparative assessment on normal keratinocytes. However, the normal skin cell line TE 353.SK that we recently obtained could not be cultured stably under the condition of our lab at this time. We are also collecting human tissue samples from patients with primary melanoma and benign nevi. Based on our data, XXX expression will be analyzed in clinical samples by immunohistochemistry, and the correlation between XXX expression and the prognosis of melanoma will be determined in our subsequent investigations. Therefore, the referee’s concern is of importance for our further study, and we will show the results in our next paper for XXX.
比如审稿人提出：补充体内实验
Tips：补充动物实验，是审稿人最爱发的一招，其实一点不令人意外。既然躲不过，就要见招拆招，如果能补上，当然是给了漂亮的回马枪；要是没有条件补，或者实验来不及，也要尽量说的委婉点，假装你确实努力了，是审稿人给的时间太短了，我根本来不及啊！
回复：We are appreciative of the reviewer’s suggestion. Indeed, it will be more profound if we get the relevant results in vivo. We have purchased 10 thymus-null BALB/c nude mice (female, age 4-6 weeks) from the Animal Center of Chinese Academy of Medical Sciences. Osteosarcoma xenografts were established in nude mice according to a previous report (Gao et al., 2009) （我们去买了若干只小鼠，按照文献的方法操作）. Briefly, control lentivirus or XXX gene shRNA-expressing lentivirus infected XXX cells (1×105) were suspended in 0.1 ml PBS and then injected subcutaneously into the proximal tibia of each anesthetized nude mice (n=5 in each group). Unfortunately, the xenografts could not grow after inoculation for three weeks （满怀欣喜的接种到动物身上，然而实验这东西，哪能一遍就成呢，我们做了一遍，结果没能成瘤，实在是悲剧了）. The limitation of technical condition may be the main reason. Also, we doubt that the cell viability could be insufficient to initiate osteosarcoma tumorigenesis in vivo due to the long-distance transport. Therefore, we seek for the editor’s tolerance and understanding. Many thanks for your kind help!
然而，补充实验，还是逃不过的一截，究竟是申请延期，再老老实实把实验做完，还是想投机取巧，argue一下，就看自己的运气了。一般情况，可以对照审稿人的意见综合权衡。高分文章，最好还是该补的全补了，低分文章，如果你觉得有80%的把握，完全可以凭你的劲爆人品成功拿下审稿人。
【SCI专栏】精彩内容预告
SCI写作编辑喜欢的语言，学会了你就不用去编修了；
Proof校对常见问题对策；
版面费支付，你该知道的Tips
解螺旋专栏项目，每周定期发布：
每周一：【CNS专栏】
每周二：【肿瘤专栏】
每周三：【组学专栏】
每周四：【SCI专栏】
每周五：【信号通路专栏】
每周六：【轻松一刻】
每周日：【实验工具专栏】
持续关注解螺旋，看专栏文章，精彩从未间断···
解螺旋线下培训正接受报名的课程
（一）Meta分析强化课程（杭州班）（6.27-6.28）
（二）线上培训：SCI插图制作技巧（可免费）
详细课程信息请点击本文左下角阅读原文查看