周末书籍分享--Animal Cell Culture哺乳动物细胞培养
Animal cells are the preferred 'cell factories' for the production of complex
molecules and antibodies for use as prophylactics, therapeutics or diagnostics.
They are used for the pro-duction of viral vectors for gene therapy. Major targets for this therapy include cancer, HIV, arthritis, cardiovascular and CNS diseases and cystic fibrosis. Animal cells are used as in vitro substrates in pharmacological and toxicological studies.
Animal Cell Culture is designed to serve as a comprehensive review of bioprocessing of animal cells for the production of biopharmaceuticals, covering the current status of both research and applications. For the student or R&D scientist or new researcher, the protocols are central to the performance of cell culture work, yet a broad understanding is essential for the translation of laboratory findings into the industrial production.
This book brings together the knowledge and experience of those who are using animal cells for the production of proteins. The chapters review the state of the art with in-depth assessments that emphasize the practical aspects of efficient operation of cell culture techniques. The book indicates those aspects of cell line develop-ment, optimization and large-scale production encountered in cell culture processes and shows how the recent development in cellular and molecular biology and omics technology can help the full realization of the potential of biotechnological exploi-tation of animal cells.
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