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【重磅!】默沙东抗PD-1肿瘤免疫治疗药物Keytruda(Pembrolizumab,MK-3475)在中国的临床试验最新进展

2016-07-31 医药研发社交平台 药时代


2016年6月8日,我们得到消息后立即发布以下文章,受到很多朋友们的关注。


【重磅消息!】默沙东抗PD-1肿瘤免疫治疗药物Keytruda(Pembrolizumab,MK-3475)在中国临床试验开始!



不少朋友与我们联系,希望了解更多信息。我们编辑立即行动,搜集最新信息,一些信息于2016年7月29日,就是前天,刚刚更新。现在汇总于此,与感兴趣的朋友们分享,希望有点滴帮助。


截止到今天,2016年7月31日,中国药监局临床试验网站显示有个临床试验,状态都是【进行中,尚未招募】。CTR20160320 针对晚期或转移性黑色素瘤CTR20160103 CTR20160097 是针对 非小细胞肺癌


序号登记号试验状态药物名称适应症试验通俗题目
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CTR20160320 针对晚期或转移性黑色素瘤,首次公示信息日期:2016-06-21。国内试验。目标入组人数 80

1、主要研究者信息

姓名郭军职称教授
电话010-88121122Emailguoj307@126.com
邮政地址北京市海淀区阜成路52号邮编100142
单位名称北京肿瘤医院



2、各参加机构信息

序号机构名称主要研究者国家省(州)城市
1北京肿瘤医院郭军中国北京北京
2吉林大学附属第一医院吴荻中国吉林长春
3邵逸夫医院潘宏铭中国浙江杭州
4中山大学附属肿瘤医院张晓实中国广东广州
5江苏省人民医院束永前中国江苏南京
6大连医科大学附属第一医院刘基巍中国辽宁大连



CTR20160103 针对非小细胞肺癌,首次公示信息日期:2016-06-06。国内试验。目标入组人数 42

主要研究者信息:

1、主要研究者信息

姓名张力职称教授
电话020-87343586Emailzhangli@sysucc.org.cn
邮政地址中国广东省广州市越秀区东风东路651号邮编510060
单位名称中山大学附属肿瘤医院



2、各参加机构信息

序号机构名称主要研究者国家省(州)城市
1中山大学附属肿瘤医院张力中国广东广州


CTR20160097 针对非小细胞肺癌,首次公示信息日期:2016-07-29。国际多中心试验。目标入组人数:总体 1240,国内 350。参加机构222个,其中中国27个

主要研究者信息:

1、主要研究者信息

姓名吴一龙职称主任医师
电话020-83827812Emailsyylwu@live.cn
邮政地址广东省广州市中山二路106号邮编510080
单位名称广东省人民医院



2、各参加机构信息

序号机构名称主要研究者国家省(州)城市
1广东省人民医院吴一龙中国广东广州
2北京协和医院张力中国北京北京
3上海市胸科医院陆舜中国上海上海
4上海市肺科医院周彩存中国上海上海
5中南大学湘雅医院胡成平中国湖南长沙
6解放军307医院刘晓晴中国北京北京
7江苏省肿瘤医院冯继峰中国江苏南京
8中国人民解放军第八一医院秦叔逵中国江苏南京
9浙江省肿瘤医院范云中国浙江杭州
10北京胸科医院刘喆中国北京北京
11北京肿瘤医院赵军中国北京北京
12哈尔滨医科大学附属肿瘤医院陈公琰中国黑龙江哈尔滨
13吉林大学第一医院李薇中国吉林长春
14吉林省肿瘤医院陈颖中国吉林长春
15中山大学附属肿瘤医院张力中国广东广州
16福建省肿瘤医院黄诚中国福建福州
17四川大学华西医院卢铀中国四川成都
18广州医科大学附属第一医院何建行中国广东广州
19中国医学科学院肿瘤医院石远凯中国北京北京
20南京军区福州总医院欧阳学农中国江苏南京
21中国人民解放军总医院胡毅中国北京北京
22浙江大学医学院附属第二医院王凯中国浙江杭州
23复旦大学附属肿瘤医院常建华中国上海上海
24第三军医大学第三附属医院何勇中国重庆重庆
25复旦大学附属中山医院张新中国上海上海
26苏北人民医院汪步海中国江苏扬州
27浙江大学医学院附属第一医院周建英中国浙江杭州
28Centro de Oncología e Investigación Buenos Aires- COIBAVarela MirtaArgentinaBuenos AiresBerazategui
29Instituto Oncologico de Cordoba (IONC)Richardet EduardoArgentinaArgentinaCordoba
30Fundacion InvestigarLerzo GuillermoArgentinaArgentinaCABA
31Centro Medico San RoqueZarba Juan JoseArgentinaArgentinaTucuman
32Centro Oncologico - Fundacion KORIZAPicon PabloArgentinaArgentinaSanta Rosa
33Sanatorio ParqueMartinengo GastonArgentinaSanta FeRosario
34Instituto de Oncologia de RosarioFein LiusArgentinaArgentinaRosario
35Centro Oncologico Riojano IntegralKaen DiegoArgentinaArgentinaLa Rioja
36Centro de Investigaciones Clinicas - Clinica ViedmaKowalyszyn RubenArgentinaArgentinaViedma
37Hospital AlemanGomez Abuin GonzaloArgentinaArgentinaBuenos Aires
38INCA Instituto Nacional do CancerVictorino Ana-PaulaBrazilRJRio de Janeiro
39Instituto do Cancer de Sao Paulo - ICESPCastro Junior GilbertoBrazilBrazilSao Paulo
40Hospital Sao Lucas - PUCRSBarrios Carlos HenriqueBrazilBrazilPorto Alegre
41Hospital de Caridade de IjuiFranke Fabio AndreBrazilRSljui
42Hospital de Clinicas de Porto Alegre - Centro de Pesquisa ClinicaAzevedo Sergio JobimBrazilBrazilPorto Alegre
43Hospital AC CamargoFreitas HelanoBrazilSPSao Paulo
44Instituto do Cancer do CearaSoares Joao Paulo HolandaBrazilCEFortaleza
45Hospital Sao JoseCosta Marcos AndreBrazilSPSao Paulo
46Fundacao Amaral CarvalhoBeato CarlosBrazilSao PauloJau
47HCor OncoLopes Junior Gilberto de LimaBrazilBrazilSao Paulo
48Hospital Sirio-LibanesShimada Andrea KazumiBrazilBrazilSao Paulo
49Hospital Paulistano / Amil Clinical ResearchCerny Carlos Alexandre SydowBrazilBela VistaSao Paulo - SP
50Hospital Israelita Albert EinsteinSmaletzBrazilBrazilSao Paulo
51Nucleo de Oncologia da BahiaSchettini Sobrinho Eldsamira da Silva MascarenhasBrazilBrazilSalvador
52Sirio-Libanes Brasília - Centro de Oncologia - Asa SulFernandes GustavoBrazilBrazilBrasilia
53Fundacao Pio XII - Hospital de Cancer de BarretosDe Marchi Pedro Rafael MartinsBrazilSao PauloBarretos
54Hosp de Base de Sao Jose do Rio PretoGirotto Gustavo ColagiovanniBrazilBrazilSao Jose do Rio Preto
55Centro Avancado de Tratamento OncologicoMurad Andre MarcioBrazilMGBelo Horizonte
56MHAT Serdika EOODKoynov KrassimirBulgariaBulgariaSofia
57UMHAT Dr. Georgi StranskiMicheva RumyanaBulgariaBulgariaPleven
58Military Medical Academy - MHATMihaylova ZhasminaBulgariaBulgariaSofia
59Tokuda Hospital SofiaPetrova AniBulgariaBulgariaSofia
60UMHAT Tsaritsa Yoana- ISUL EADKoleva MarchelaBulgariaBulgariaSofia
61Sunnybrook Health Sciences, Odette Cancer CentreCheng SusannaCanadaONToronto
62CSSS Champlain Charles LemoyneSperanza GiovannaCanadaQCGreenfield Park
63Juravinski Cancer CentreJuergens Rosalyn AnneCanadaONHamilton
64BCCA-Vancouver Island Cancer CentreKsienski DoranCanadaBCVictoria
65Clinica Alemana de TemucoRey FelipeChileChileTemuco
66Centro Internacional de Estudios Clinicos, CIECAren OsvaldoChileChileSantiago
67Fundacion Arturo Lopez PerezCaglevic ChristianChileChileSantiago
68Centro de Cancer Nuestra Senora de la EsperanzaGalindo HectorChileRegion MetropolitanaSantiago
69Instituto De Cancerologia S.A.Gomez Wolff LuisColombiaColombiaMedellin
70Fundacion Valle del LiliZambrano AngelaColombiaValle del CaucaCali
71Clinica del Country, Centro de InvestigaciónCardona AndresColombiaCundinamarcaBogota
72Fakultni nemocnice OstravaRoubec JaromirCzech RepublicCzech RepublicOstrava-Poruba
73Nemocnice KyjovKolman PetrCzech RepublicCzech RepublicKyjov
74Fakultni Poliklinika VFNPetruzelka LubosCzech RepublicCzech RepublicPraha 2
75Multiscan s.r.o.Vanasek JaroslavCzech RepublicCzech RepublicPardubice
76Fakultni Nemocnice OlomoucKolek VitezslavCzech RepublicCzech RepublicOlomouc
77Nemocnice Na BulovceHavel LiborCzech RepublicCzech RepublicPraha 8
78Oblastni nemocnice Mlada Boleslav, a.s.Vlasek TomasCzech RepublicCzech RepublicMlada Boleslav
79Fakultni nemocnice MotolKoubkova LeonaCzech RepublicCzech RepublicPraha 5
80Thomayerova nemocniceHavel LiborCzech RepublicCzech RepublicPraha 4
81AS Ida - Tallinna KeskhaiglaKuusk GerliEstoniaEstoniaTallinn
82SA Tartu Ulikooli KliinikumJaal JanaEstoniaEstoniaTartu
83Grupo Médico AngelesCastro HugoGuatemalaGuatemalaGuatemala
84Oncomedica S.A.Lopez KarlaGuatemalaGuatemalaGuatemala
85Medical SolutionAvendano OscarGuatemalaGuatemalaGuatemala
86Private Clinic Mario Fredy SandovalSandoval MarioGuatemalaGuatemalaGuatemala
87Prince of Wales HospitalMok TonyHong KongHong KongShatin
88Tuen Mun HospitalLo Sing HungHong KongHong KongTuen Mun
89Queen Mary HospitalHo Chung Man JamesHong KongHong KongPokfulam
90Orszagos Koranyi TBC es Pulmonologiai IntezetOstoros GyulaHungaryHungaryBudapest
91Jasz - Nagykun Szolnok megyei Hetenyi Geza Korhaz - RendelointezetCsoszi TiborHungaryHungarySzolnok
92Tokyo Metropolitan Komagome HospitalHosomi YukioJapanTokyoTokyo
93Kurume University HospitalYamada KazuhikoJapanFukuokaKurume
94National Hospital Organization Kyushu Medical CenterIchiki MasaoJapanFukuokaFukuoka
95Osaka City University HospitalKawaguchi TomoyaJapanOsakaOsaka
96Osaka Medical College HospitalFujisaka YasuhitoJapanOsakaTakatsuki
97Juntendo University HospitalTakahashi KazuhisaJapanTokyoTokyo
98Kanazawa University HospitalKasahara KazuoJapanIshikawaKanazawa
99Osaka Medical Center for Cancer and Cardiovascular DiseasesImamura FumioJapanOsakaOsaka
100Kanagawa Cancer CenterMurakami ShujiJapanKanagawaYokohama
101Osaka Prefectural Medical Center for Respiratory and Allergic DiseasesHirashima TomonoriJapanOsakaHabikino
102Kurashiki Central HospitalYoshioka HiroshigeJapanOkayamaKurashiki
103Niigata Cancer Center HospitalTanaka HiroshiJapanNiigataNiigata
104National Hospital Organization Himeji Medical CenterNakahara YasuharuJapanHyogoHimeji
105Kyorin University HospitalYokoyama TakumaJapanTokyoMitaka
106Gifu Municipal HospitalSawa ToshiyukiJapanGifuGifu
107Hiroshima City Hiroshima Citizens HospitalIwamoto YasuoJapanHiroshimaHiroshima
108Nippon Medical School HospitalKubota KaoruJapanTokyoTokyo
109Kyoto Katsura HospitalNishimura TakashiJapanKyotoKyoto
110Kawasaki Hospital, Kawasaki Medical SchoolTakigawa NagioJapanOkayamaOkayama
111Teikyo University HospitalSeki NobuhikoJapanTokyoTokyo
112National Hospital Organization Nagoya Medical CenterSaka HideoJapanAichiNagoya
113Toranomon HospitalKishi KazumaJapanTokyoTokyo
114The Cancer Institute Hospital of JFCRHoriike AtsushiJapanTokyoTokyo
115Kansai Medical University Hirakata HospitalTorii YoshitaroJapanOsakaHirakata
116Tokyo Medical University HospitalOhira TatsuoJapanTokyoTokyo
117National Hospital Organization Yamaguchi Ube Medical CenterAoe KeisukeJapanYamaguchiUbe
118Institute of Biomedical Research and Innovation HospitalKatakami NobuyukiJapanHyogoKobe
119Sendai Kousei HospitalSugawara ShunichiJapanMiyagiSendai
120Okayama University HospitalHotta KatsuyukiJapanOkayamaOkayama
121Riga East Clinical University - Latvian Oncology CenterKudaba IvetaLatviaLatviaRiga
122Liepaja Regional HospitalStara ZinaidaLatviaLatviaLiepaja
123P. Stradina Clinical University HospitalPurkalne GuntaLatviaLatviaRiga
124Nacionalinis Vezio Institutas.Cicenas SauliusLithuaniaLithuaniaVilnius
125LSMUL Kauno KlinikosZemaitis MariusLithuaniaLithuaniaKaunas
126Klaipedos universitetine ligonine, Chemoterapijos skyriusCesas AlvydasLithuaniaLithuaniaKlaipeda
127Hospital Pulau PinangOng Choo KhoonMalaysiaPulau PinangPenang
128University Malaya Medical CentreLiam Chong KinMalaysiaMalaysiaKuala Lumpur
129Beacon International Specialist CentreTho Lye MunMalaysiaSelangorPetaling Jaya
130Hospital Tengku Ampuan AfzanHow Soon HinMalaysiaPahangKuantan
131Oaxaca Site Management Organization SCHernandez CarlosMexicoMexicoOaxaca
132Centro Oncologico de Chihuahua (COC)Bustamante Valles Flor de TheMexicoChihuahuaChihuahua
133Instituto Nacional de CancerologiaArrieta Rodriguez OscarMexicoMexicoMexico City
134Instituto Oncologico MirafloresSalas S. JorgePeruLimaLima
135Instituto Nacional de Enfermedades NeoplasicasMas LuisPeruLimaLima
136Hospital Nacional Cayetano Heredia [Lima, Peru]Tejada B. HermesPeruLimaSan Martin de Porres
137Clínica Internacional - Sede San BorjaVera LuisPeruLimaSan Borja
138Veteran's Memorial Medical CenterGalvez ChristinaPhilippinesNCRQuezon
139Makati Medical CenterEdusma-Dy ReginaPhilippinesPhilippinesMakati
140Cebu Doctors University HospitalTan Chun Bing JerryPhilippinesPhilippinesCebu City
141Lung Center of the PhilippinesLadrera Guia Elena ImeldaPhilippinesPhilippinesQuezon
142Centrum Onkologii-Instytut im. Marii Sklodowskiej-CurieKowalski DariuszPolandPolandWarszawa
143MED-POLONIA Sp. z o.o.Ramlau RodrygPolandPolandPoznan
144Uniwersyteckie Centrum KliniczneJassem JacekPolandPolandGdansk
145Wojewodzki Szpital Specjalistyczny im. M. Kopernika w LodziKalinka-Warzocha EwaPolandPolandLodz
146Przychodnia Lekarska KomedKaraszewska BoguslawaPolandPolandKonin
147Samodzielny Publiczny Zespol Gruzlicy i Chorob PlucKazarnowicz AndrzejPolandPolandOlsztyn
148Szpital Wojewodzki w GdyniLesniewski Kmak KrzysztofPolandPolandGdynia
149COT Centro Oncologico do Triangulo MineiroLopes ValeriaBrazilBrazilBrazil
150Clinica Colsanitas S.A, Sede Clinica Universitaria ColombiaDuarte RicardoColombiaColombiaColombia
151Bekes Megyei Kozponti Korhaz Pandy Kalman TagkorhazaPiko BelaHungaryHungaryHungary
152Centro Hospitalar e Universitario de CoimbraBarata FernandoPortugalPortugalCoimbra
153Fundacao ChampalimaudGil NunoPortugalPortugalLisboa
154Centro Hospitalar de S. Joao E.P.E.Hespanhol VenceslauPortugalPortugalPorto
155Centro Hospitalar do Porto, E.P.E. - Hospital Geral de Sto. AntonioAraujo AntonioPortugalPortugalPorto
156Oncolab SRLCherciu NellyRomaniaRomaniaCraiova
157Policlinica Oncomed SRLSirbu DanielaRomaniaRomaniaTimisoara
158Spitalul Judetean de UrgentaGanea DoinaRomaniaRomaniaSuceava
159Spitalul Clinic Judetean de Urgenta Cluj [Oncologie Medical]Turdean MariaRomaniaClujCluj-Napoca
160Institutul Oncologic Prof. Dr. Alexandru TrestioreanuAlexandru AureliaRomaniaSector 2Bucharest
161Spital PDR-MedlifeCiurescu DanielRomaniaBrasovBrasov
162Institutul Regional de Oncologie IasiMiron LucianRomaniaRomaniaIasi
163Municipal Clinical Oncology CenterKaraseva NinaRussiaRussiaSaint Petersburg
164Russian Oncological Research Center n.a. N.N.Blokhin of RAMSLaktionov KonstantinRussiaRussiaMoscow
165Kurskiy Regional Oncology DispensaryLifirenko IgorRussiaRussiaKursk
166Republican Clinical Oncology Dispensary of Tatarstan MoHKuzmin AlexeyRussiaRussiaKazan
167Udmurtia Republic Regional Clinical Oncology DispensaryEmelyanov SergeyRussiaRussiaIzhevsk
168Bashkortostan Republican Clinical Oncology DispensaryLipatov OlegRussiaRussiaUfa
169Nizhniy Novgorod Region Oncology DispensaryMatrosova MarinaRussiaRussiaNizhniy Novgorod
170Scientific Research Oncology Institute n.a. N.N.PetrovPoltoratsky ArtemRussiaRussiaSaint Petersburg
171Altay Regional Oncology DispensaryLazarev SergeyRussiaRussiaBarnaul
172Siberian Regional Medical Centre of FMBA of RussiaZarubenkov OlegRussiaRussiaNovosibirsk
173Belgorod Regional Oncology DispensaryKuzina LyudmilaRussiaRussiaBelgorod
174PRETORIA ACADEMIC HOSPITAL - ONCOLOGY (OPD)Dreosti LydiaSouth AfricaGautengPretoria
175The Medical Oncology Centre of RosebankRapoport BernardoSouth AfricaGautengJohannesburg
176Wits Donald Gordon Clinical Trial SiteRuff PaulSouth AfricaSouth AfricaJohannesburg
177Rainbow Oncology CentreSzpak WaldemarSouth AfricaKwazulu-Natal (South Africa)Durban
178Dr G.A. Landers Specialist OncologistLanders GregorySouth AfricaKwazulu NatalDurban
179Mary Potter Oncology CentreCohen GrahamSouth AfricaGautengPretoria
180Department of Radiation OncologyShepherd LucindaSouth AfricaWestern CapeCape Town
181GVI Rondebosch OncologyHart GregorySouth AfricaWestern CapeCape Town
182Oncology CentreHall JacquelineSouth AfricaSouth AfricaCape Town
183Department of OncologyJordaan ChristaSouth AfricaSouth AfricaBloemfontein
184Samsung Medical CenterAhn Myung-JuSouth AfricaSouth AfricaSeoul
185Severance Hospital, Yonsei University Health SystemCho Byoung ChulSouth AfricaSouth AfricaSeoul
186Norrlands UniversitetssjukhusBergstrom PerSwedenSwedenUmea
187Skanes universitetssjukhusOhman RonnySwedenSwedenLund
188Hopital Fribourgeois - Freiburger SpitalBetticher DanielSwitzerlandSwitzerlandFribourg
189Inselspital Universitatsspital BernOchsenbein AdrianSwitzerlandSwitzerlandBern
190Universitaetsspital BaselZippelius AlfredSwitzerlandSwitzerlandBasel
191Taipei Veterans General HospitalTsai Chun-MingTaiwanTaiwanTaipei
192China Medical University HospitalHsia Te-ChunTaiwanTaiwanTaichung
193Taichung Veterans General HospitalChang Gee-ChenTaiwanTaiwanTaichung
194National Cheng Kung University HospitalSu Wu-ChouTaiwanTaiwanTainan
195National Taiwan University HospitalYang Chih-HsinTaiwanTaiwanTaipel
196Phramongkutklao HospitalSeetalarom KasanThailandThailandBangkok
197Chulalongkorn HospitalSriuranpong ViroteThailandThailandBangkok
198Ramathibodi Hospital [Bangkok, Thailand]Ativitavas TouchThailandThailandBangkok
199Siriraj Hosp., Faculty of MedicineSrimuninnimit VichienThailandThailandBangkok
200Khon Kaen UniversitySookprasert AumkhaeThailandThailandBangkok
201Istanbul Uni. Cerrahpasa Tip FakultesiTurna ZeynepTurkeyTurkeyAnkara
202Bezmialem Vakif UniversityGumus MahmutTurkeyTurkeyIstanbul
203Baskent Universitesi Ankara HastanesiAltundag OzdenTurkeyTurkeyAnkara
204Hacettepe University Medical OncologyErman MustafaTurkeyTurkeyAnkara
205Marmara Uni.Egi.ve Ars. Hast.Yumuk FuldenTurkeyTurkeyIstanbul
206Ankara Universitesi Tip FakultesiCay Senler FilizTurkeyTurkeyAnkara
207Baskent Universitesi Adana Uygulama ve Arastirma MerkeziOzyilkan OzgurTurkeyTurkeyAdana
208Ege Uni. Tip FakultesiGoker ErdemTurkeyTurkeyIzmir
209Zakarpattia Regional clinical oncology centerRusyn AndriiUkraineUkraineUzhgorod
210Lviv State Oncology Regional Treatment and Diagnostic CentreShparyk YaroslavUkraineUkraineLviv
211Regional Clinical Onco Dispensary_ State Medical UniversityIvashchuk OleksandrUkraineUkraineChernivtsi
212Volyn Regional Oncological DispensaryAndrusenko OrestUkraineUkraineLutsk
213Vinnytsia Regional Clinical Oncology DispensaryShevnya SergiiUkraineUkraineVinnytsia
214Dnipropetrovsk City Multidiscipline Clinical Hosp.4 of DRCBondarenko IgorUkraineUkraineDnipropetrovsk
215RMI Sumy Regional Clinical Oncology DispensaryVynnychenko IgorUkraineUkraineSumy
216Kyiv City Clinical Oncological CenterPonomarova OlgaUkraineUkraineKyiv
217MI Kryviy Rih Center of Dnipropetrovsk Regional CouncilAdamchuk GrigoryUkraineUkraineKryviy Rih
218PP PPC Acinus - Medical and Diagnostic CentreUrsol GrygoriyUkraineUkraineKirovograd
219MI Odessa Regional Oncological CentreTrukhyn DmytroUkraineUkraineUkraine
220Ho Chi Minh City Oncology HospitalPham Xuan DungVietnamHo Chi MinhHo Chi Minh
221Vietnam National Cancer HospitalNguyen Tien QuangVietnamHa NoiHa Noi
222Bach Mai HospitalMai Trong KhoaVietnamHa NoiHa Noi

我们衷心感谢

默沙东

为中国及世界医药研发事业做出的卓越奉献!

辉煌的125年!

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【重磅消息!】默沙东抗PD-1肿瘤免疫治疗药物Keytruda(Pembrolizumab,MK-3475)在中国临床试验开始!

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