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NCCN T细胞淋巴瘤临床实践指南2017.2版(6)

2017-09-01 洪振亚 指南解读

目录


支持治疗(LYMP-A)

LYMP-A(1/2)

肿瘤溶解综合征及其治疗

注解:

a.有数据支持固定剂量的拉布立酶在成年患者中非常有效。

LYMP-A(2/2)

单克隆抗体治疗与病毒再激活以及甲氨蝶呤相关的肾功能不全


非霍奇金淋巴瘤卢加诺响应标准(LYMP-B)

LYMP-B(1/3)

完全缓解与部分缓解

经许可转载。©美国临床肿瘤学会。保留所有权利。Cheson B, Fisher R, Barrington S, et al.Recommendations for Initial Evaluation, Staging and Response Assessment of Hodgkin and Non-Hodgkin Lymphoma —the Lugano Classification.J Clin Oncol 2014;32:3059-3067.

LYMP-B(2/3)

疾病稳定与疾病进展

经许可转载。©美国临床肿瘤学会。保留所有权利。Cheson B, Fisher R, Barrington S, et al.Recommendations for Initial Evaluation, Staging and Response Assessment of Hodgkin and Non-Hodgkin Lymphoma —the Lugano Classification.J Clin Oncol 2014;32:3059-3067.

LYMP-B(3/3)

注解

经许可转载。©美国临床肿瘤学会。保留所有权利。Cheson B, Fisher R, Barrington S, et al.Recommendations for Initial Evaluation, Staging and Response Assessment of Hodgkin and Non-Hodgkin Lymphoma —the Lugano Classification.J Clin Oncol 2014;32:3059-3067.


放疗原则(LYMP-C)

LYMP-C(1/4)

放疗总则

注解:

a.见参考文献(LYMP-C 4/4)。

LYMP-C(2/4)

靶区

注解:

a.见参考文献(LYMP-C 4/4)。

LYMP-C(3/4

常用剂量

注解:

a.见参考文献(LYMP-C 4/4)。

LYMP-C(4-4)

参考文献

Filippi AR, Ragona R, Fusella M, et al. Changes in breast cancer risk associated with different volumes, doses, and techniques in female Hodgkin lymphoma patients treated with supra-diaphragmatic radiation therapy. Pract Radiat Oncol 2013;3:216-222.

Girinsky T, Pichenot C, Beaudre A, et al. Is intensity-modulated radiotherapy better than conventional radiation treatment and three-dimensional conformal radiotherapy for mediastinal masses in patients with Hodgkin's disease, and is there a role for beam orientation optimization and dose constraints assigned to virtual volumes? Int J Radiat Oncol Biol Phys 2006;64:218-226.

Horning SJ, Weller E, Kim K, et al. Chemotherapy with or without radiotherapy in limited-stage diffuse aggressive non-Hodgkin's lymphoma: Eastern Cooperative Oncology Group study 1484. J Clin Oncol 2004;22:3032-3038.

Hoskin PJ, Díez P, Williams M, et al. Recommendations for the use of radiotherapy in nodal lymphoma. Clin Oncol (R Coll Radio l) 2013;25:49-58.

Illidge T, Specht L, Yahalom J, et al. Modern radiation therapy for nodal non-Hodgkin lymphoma-target definition and dose guidelines from the International Lymphoma Radiation Oncology Group. Int J Radiat Oncol Biol Phys 2014 1;89:49-58.

Li YX, Wang H, Jin J, et al. Radiotherapy alone with curative intent in patients with stage I extranodal nasal -type NK/T-cell lymphoma. Int J Radiat Oncol Biol Phys 2012;82:1809-1815.

Miller TP, Dahlberg S, Cassady JR, et al. Chemotherapy alone compared with chemotherapy plus radiotherapy for localized intermediate- and high-grade non-Hodgkin's lymphoma. N Engl J Med 1998;339:21-26.

Nieder C, Schill S, Kneschaurek P, Molls M. Influence of different treatment techniques on radiation dose to the LAD coronary artery. Radiat Oncol 2007;2:20.

Wang H, Li YX, Wang WH, et al. Mild toxicity and favorable prognosis of high-dose and extended involved-feld intensity-modulated radiotherapy for patients with early-stage nasal NK/T-cell lymphoma. Int J Radiat Oncol Biol Phys 2012;82:1115-1121.

Yahalom J, Illidge T, Specht L, Hoppe RT, et al. Modern Radiation Therapy for Extranodal Lymphomas: Field and Dose Guidelines from the International Lymphoma Radiation Oncology Group. Int J Radiat Oncol Biol Phys 2015;92:11-31.


分类和分期(ST-1,2,3

ST-1

成熟B细胞肿瘤WHO分类

ST-2

T细胞、NK细胞肿瘤WHO分类

ST-3

安阿伯分期系统的卢加诺修订版

注解:

*.亲和淋巴瘤的疾病程度由PET-CT确定,非亲和淋巴瘤的疾病程度由CT确定

注:扁桃体、韦氏环、脾被视为淋巴结组织

**.II期巨块型按局限性还是进展疾病治疗可由组织学和多种预后因素来确定

A类与B类对比已从安阿伯分期的卢加诺修订中删除。

经许可转载。©美国临床肿瘤学会。保留所有权利。Cheson B, Fisher R, Barrington S, et al.Recommendations for Initial Evaluation, Staging and Response Assessment of Hodgkin and Non-Hodgkin Lymphoma —the Lugano Classification.J Clin Oncol 2014;32:3059-3067.


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