特邀学术报告︱神经精神药理的反转化研究(胡霁,特聘教授,上海科技大学,4月1日晚8:00-9:00)
责编︱王思珍,方以一
(第一期)
主讲人:胡霁,特聘教授,上海科技大学
时间:2023年4月1日(周六)20:00-21:00(北京时间)
主持人:王强强(王思珍),主编
会议ID:280-399-427(腾讯会议)
报告摘要(Abstract)
1 in every 8 people, or 970 million people around the world were living with a psychiatric disorder. However, medication for psychiatric disorders has not been updated for 50 years, partly because of a lack of knowledge about the etiology of mental illness, which makes translational research inefficient. We are applying a reverse-translational approach to gain insight into the neurobiological mechanisms underlying human psychiatric disorders and the effects of pharmacological treatments. We have found that atypical antipsychotics antagonize GABAA receptors in the ventral tegmental area GABA neurons to relieve psychotic behaviors. Also, we reported that propofol actively and directly binds to the dopamine transporter (DAT), but not the serotonin transporter, which contributes to the rapid relief of anhedonia.
胡霁,教育部长江学者特聘教授。上海科技大学研究员/博士生导师,助理院长。目前担任中国神经科学会应激神经生物学分会副主任委员,中国神经科学会认知神经生物学分会副主任委员。获得国家青年千人,自然科学基金面上项目,自然科学基金优秀青年项目,自然科学基金重大研究计划,自然科学基金重大项目,科技部973计划支持。研究成果以通讯作者在Nature、Neuron、Current Biology、Science Advances等国际学术期刊发表系列论文。获得重庆市科技进步一等奖,中科院教学成果二等奖,上海市教学成果特等奖。
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