COVID-19 patients with diarrhea likely to have severe symptoms

COVID-19 patients with diarrhea more likely to have severe symptoms

Researchers have found that more novel coronavirus disease (COVID-19) patients with diarrhea showed severe symptoms of pneumonia than those without diarrhea, according to a recently published research article in the journal Lancet Gastroenterology and Hepatology.

The researchers from the Sixth Affiliated Hospital of Sun Yat-sen University and its Research Institute of Gastroenterology examined the intestinal symptoms of patients with COVID-19 from multiple medical centers in China.

They collected and analyzed data from 232 patients who were tested positive for COVID-19 and admitted to 14 hospitals in provinces of Guangdong, Hubei and Jiangxi from January 19 to March 6. Two patients with pre-existing digestive diseases were excluded from the analysis.

The patients' most common symptoms at the onset of illness were fever, cough and sputum production. Diarrhea was observed in 49 patients, or 21 percent, according to the research article which said that the patients with diarrhea were older and more likely to have comorbidities than those without diarrhea.

The researchers also discovered that more patients with diarrhea showed severe symptoms of pneumonia than those without. Although there was no correlation between diarrhea and oxygen supplementation, a greater proportion of patients with diarrhea required ventilator support and admission to intensive care, said the article.

They did not observe a correlation between diarrhea and the use of antiviral medicine or antibiotics.

The analysis did not cover the data on the prevalence of asymptomatic COVID-19.

The researchers also pointed out that the medicines like antivirals, lopinavir and ritonavir are known to cause diarrhoea.

新冠肺炎患者出现胃肠症状更易发展为重症

新冠肺炎患者若出现胃肠症状将有更高几率发展为重症。中山大学附属第六医院兰平教授团队在《柳叶刀》胃肠病和肝病子刊上，针对“武汉以外新冠肺炎住院患者的胃肠症状”发表了一项关于新型冠状病毒的胃肠道症状原创研究论文，此项多中心回顾性研究由中山六院、中山大学胃肠病学研究所和全国多家医院及研究机构合作完成。

虽然新冠病毒引起的疾病名称是肺炎，但该病毒的受体在全身几乎所有组织中都有表达，尤其在胃肠道有很高的表达。“假如忽略胃肠症状，将有可能阻碍部分新冠病人的确诊，并加剧病毒经粪口传播的危害。”兰平说。基于此，团队和湖北、广东、江西的多个医院建立了合作关系，收集了232位匿名新冠病人的病历。在研究中发现，21%的新冠病毒感染者在住院期间出现了腹泻症状，大大高于原先报道中的3%。同时，还发现很多新冠病毒感染患者有血便的症状。这些结果均支持了新冠病毒经由消化道的传播机制。

TIANJIN: 

No new coronavirus cases reported, 

2 Patients discharged

Workers make face masks at the workshop of a biological engineering company in Qingdao, east China's Shandong Province

As of April 22 18:00, there were no new imported cases of novel coronavirus reported in the city. So far, of all the 53 imported cases, 45 have been discharged upon recovery and 8 are still hospitalized, including one in critical condition.

No imported suspected cases are undergoing test.

No new locally transmitted cases or suspected cases were reported on Monday.

3 asymptomatic infection cases are undergoing medical observation right now, the health commission said.

天津无新增！治愈出院2人

4月22日6时至18时，我市无新增报告境外输入新冠肺炎确诊病例。累计报告境外输入确诊病例53例（中国籍49例、美国籍2例、法国籍1例、菲律宾籍1例），治愈出院45例，在院8例（重型1例、普通型5例、轻型2例）。

4月22日6时至18时，我市无新增报告本地新冠肺炎确诊病例，累计报告本地新冠肺炎确诊病例136例，其中男性73例，女性63例；治愈出院133例，死亡3例。

4月22日6时至18时，我市无新增报告无症状感染者。累计报告5例（境外输入4例），其中转为确诊病例2例、尚在医学观察3例。

经市专家组讨论，第30例、第49例境外输入确诊病例，符合出院标准，于今日出院，转入集中隔离医学观察点。

截至目前，全市无现存疑似病例，累计排查密切接触者3158人，尚有150人正在接受医学观察。

Continental powertrain unit to set up Tianjin R&D center

An artist's rendition of the planned research and development center of Vitesco Technologies in Tianjin

Vitesco Technologies, the powertrain business of Continental, has announced that it will build a research and development center in Tianjin.

Vitesco Technologies will develop technologies for hybrid and electric powertrains in the new R&D center, which is scheduled for completion in 2021.

The company's decision is based on China's position as the world's largest new-energy vehicle market as well as broad government support.

The new R&D center will include a lab where electric drive technologies can be tested and validated with a wide array of advanced test facilities. It will cover systems, software, electronics, mechatronics as well as supporting functions and attracts talent from all over the world.

Vitesco Technologies said the new R&D center will forge even closer links to local customers in the world’s largest automotive market and support the development of vehicles with electrification technologies.

Vitesco Technologies is a Powertrain Division of Continental AG. In 2019, Continental announced to spin-off its Powertrain division with the purpose to give it more freedom to respond to market demands. A final decision on the spin-off waits confirmation from Continental annual shareholders’ meeting.

动力总成公司纬湃科技将在天津建立全新的研发中心

大陆集团下属动力总成公司纬湃科技(Vitesco Technologies)将在天津建立一个全新的研发中心。目前，公司已与天津经济技术开发区管委会签署相关协议。新研发中心预计于2021年落成，这里将成为纬湃科技混合动力及电气化动力总成技术的研发基地。

新的研发中心总建筑面积约9000平方米。除办公楼外，研发中心还设有一个测试实验室，其中配套各种测试设备用于电力驱动技术的测试和验证。

纬湃科技在天津拥有一家建有高度自动化生产线的工厂，并于2019年10月投产第三代电驱动系统，该系统高度集成了电机、电控和减速器，减少大量连接线束并配备了最新的液冷技术，其重量不到80公斤，让整个电驱动总成更轻、更紧凑、成本更低。率先应用该系统的车型包括标致e-208(参数|询价)和欧宝Corsa-e，以及北京现代的昂希诺纯电动和菲斯塔纯电动版车型。

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