2019年9月12日,来自美国基因泰克公司的Vishva M. Dixit教授在Nature上发表了题为Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis 的研究,报道了caspase-8可以通过切割RIPK1蛋白从而限制凋亡和坏死信号的过度激活,维持胚胎的正常发育。
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