学而 | 生命科学 · 下周讲座预告 3.24-3.30
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□Mitochondrial Calcium Signaling
题目：Mitochondrial Calcium Signaling
主讲人：Gyorgy Hajnoczky, M.D., Ph.D.
讲座地点：北京大学英杰交流中心306会议室
讲座日期：2018-03-27
讲座时间：10:00 — 11:30
联系人： 陈晓伟 (Tel. 6276-8919)
□Acetylcholinesterase: 25 Years Since the 3D Structure was Determined: What Have We Learned?
题目: Acetylcholinesterase: 25 Years Since the 3D Structure was Determined: What Have We Learned?
主讲人：Joel L. Sussman, Ph.D.
讲座地点：金光生命科学大楼311会议室
讲座日期：2018-03-27
讲座时间：10:00 — 11:00
联系人：苏晓东教授
□A Family of Metabolism-sensitive Lysine Acylation Pathways: Biochemistry, epigenetics and pathophysiology
题目：A Family of Metabolism-sensitive Lysine Acylation Pathways: Biochemistry, epigenetics and pathophysiology
主讲人：Yingming Zhao, Ph.D.
讲座地点：邓佑才报告厅，北京大学金光生命科学大楼
讲座日期：2018-03-29
讲座时间：13:00 — 14:00
联系人：王初
□Novel human pluripotent stem cell derived 2D neurons and 3D brain organoids models to study neurological disorders
题目：Novel human pluripotent stem cell derived 2D neurons and 3D brain organoids models to study neurological disorders
主讲人：Jing Fan, Ph.D.
讲座地点：北京大学英杰交流中心306W
讲座日期：2018-03-29
讲座时间：16:00 — 17:00
联系人：赵扬 (Tel.6276-6138)
□PIN-ning down the function of D6PK protein kinases in auxin transport regulation
题目：PIN-ning down the function of D6PK protein kinases in auxin transport regulation
主讲人：Prof. Dr. Claus Schwechheimer
讲座地点：生命科学学院邓祐才报告厅
讲座日期：2018-03-30
讲座时间：13:00 — 14:30
联系人：瞿礼嘉教授
摘要：
The biosynthesis and proper distribution of the phytohormone auxin within the plant influences almost every aspect of plant growth and development. To the largest extent, differences in the morphology between plants are the results of differential auxin distribution and auxin actions at the level of individual plants cells. Whereas auxin transport from cell to cell and within a plant had for a long time been inferred solely based on the polar distribution of PIN auxin exporters, we have recently shown that PINs require activation by protein kinases, such as the D6 PROTEIN KINASE, to become active auxin transporters. I will describe the biochemistry of D6PK and mechanisms that are required for targeting D6PK to the plasma membrane and the PINs. I will also present data that challenge the current view of how PIN polarity is controlled by phosphorylation. Finally, I will highlight some other regulatory functions of D6PK that are independent of PIN-dependent auxin transport control.
This work is funded through grants from the Deutsche Forschungsgemeinschaft
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