The Innovation | Volume 4 Issue 5 Live Now

Volume 4 Issue 5

2023年09月11日

The Innovation

第四卷第五期正式出版

On the Cover

Meat quality, an economically important trait in pig industry, is a determining factor in the overall acceptability of eating quality, which is closely related to fatty acid (FA) compositions. Muscle FA composition is governed by heredity, age, diet, and feeding environment. In recent decades, the role of the gut microbiota in host lipid metabolism has been widely confirmed in germ-free models. On this cover story, scientists transplanted obese Ningxiang pigs’ fecal microbiota into the lean Duroc Landrace Yorkshire pigs, leading to higher muscle FA contents and meat quality. Obese Ningxiang pig-derived Lactobacillus reuteri has been identified as a key microbiota to manipulate the muscle FA deposition by targeting SLC22A5-mediated carnitine metabolism. These novel findings provide a new potential microbial strategy for muscle FA-based meat quality management.

Illustrated by Jie Yin, Qiang Wang, Huiqian Luo, Enke Liu, Fengliang Dong, Wei Zhang, Peijun Zhang, Lei Qian, Xingguo Huang, Yulong Yin, Xianxi Dong, Meng Liang and Ke Chen.

本期封面主题

肠道微生物调控猪肌肉脂肪酸沉积（Gut microbiota-mediated muscle fatty acid deposition）。北宋大诗人苏轼留有多篇关于猪肉的诗句，其中“待他自熟莫催他，熟度足时他自美”和“五日一见花猪肉，十日一遇黄鸡粥”表现了对猪肉的喜爱。猪肉品质作为养猪业重要的一个经济性状是饮食质量整体可接受性的决定因素。猪肉品质与肌肉脂肪酸含量和组成密切相关，其中肌肉脂肪酸受遗传、年龄、饮食和喂养环境的影响。近几十年来，肠道微生物群在宿主脂质代谢中的作用已在无菌动物模型中得到广泛证实。在肠道微生物与猪脂肪代谢互作研究中，来自湖南农业大学的科学家将脂肪型宁乡猪的粪便微生物移植到瘦肉型杜长大猪中，结果提高肌肉脂肪酸含量和肉品质。脂肪型宁乡猪来源菌群，尤其是罗伊氏乳杆菌主要通过靶向抑制SLC22A5介导的肉碱代谢来调控肌肉脂肪酸沉积。以上创新性结果为基于肌肉脂肪酸调控的肉品质提升提供了一种新的潜在微生物策略。

本文包含9个部分，涉及8图6表 

(注: 文末有抽奖)

文末抽奖送精美期刊～

1. Article Types  | 文章类别

Table 1 Article Types

Table 2 Authors’ Countries and Citation

本期作者来自全球10个国家: Australia, Canada, China, Italy, Korea, Malaysia, Netherlands, Sweden, UK, USA。2020-2023年已发表426篇文章；作者来自全球55个国家，目前被全球136个国家的作者引用。

2. Contents | 本期内容

本期内容覆盖领域：物理、生命、地学、医学、材料、交叉科学等。共发表25篇文章，包括1篇Editorial、1篇 News & Buzz、1篇Letter、1篇 Perspective、 2篇Translational Patent、9篇Commentary、3篇Article、4篇Report和3篇Review。

2.1

Editorial

National botanical gardens at the forefront of global plant diversity conservation

2.2

News & Buzz

Phytolith evidence reveals the origin of angiosperm leaf eating habits among ancient Cretaceous birds

2.3

Letter

Characterization of intratumor microbiome in cancer immunotherapy

2.4

Perspective

Unwavering excellence: How to be a competent cardiovascular doctor in “panvascular medicine +”

原文链接：https://www.cell.com/the-innovation/fulltext/S2666-6758(23)00117-0

DOI: https://doi.org/10.1016/j.xinn.2023.100489

2.5

Translational Patent

OvaRePred: Online tool for predicting the age of fertility milestones

原文链接：https://www.cell.com/the-innovation/fulltext/S2666-6758(23)00118-2

DOI: https://doi.org/10.1016/j.xinn.2023.100490

AI-link omnipotent pathological robot: Bridging medical meta-universe to real-world diagnosis and therapy

2.6

Commentaries

Learning from the heaviest ancient whale

原文链接：https://www.cell.com/the-innovation/fulltext/S2666-6758(23)00129-7

DOI: https://doi.org/10.1016/j.xinn.2023.100501

The potential of engineered multifunctional quantum dots for macrophage theranostics

原文链接：https://www.cell.com/the-innovation/fulltext/S2666-6758(23)00120-0

DOI: https://doi.org/10.1016/j.xinn.2023.100492

Is there a pure quantum spin liquid?

Promise to electrically pumped colloidal quantum dot lasers

原文链接：https://www.cell.com/the-innovation/fulltext/S2666-6758(23)00126-1

DOI: https://doi.org/10.1016/j.xinn.2023.100498

Increased sandstorm frequency in North China in 2023: Climate change reflection on the Mongolian plateau

原文链接：https://www.cell.com/the-innovation/fulltext/S2666-6758(23)00125-X

DOI: https://doi.org/10.1016/j.xinn.2023.100497

Unequal urban heat burdens impede climate justice and equity goals

原文链接：https://www.cell.com/the-innovation/fulltext/S2666-6758(23)00116-9

DOI: https://doi.org/10.1016/j.xinn.2023.100488

Ecosystem quality-based management and the development of a new eco-friendly economy

原文链接：https://www.cell.com/the-innovation/fulltext/S2666-6758(23)00119-4

DOI: https://doi.org/10.1016/j.xinn.2023.100491

All-perovskite tandem solar cells gallop ahead

原文链接：https://www.cell.com/the-innovation/fulltext/S2666-6758(23)00121-2

DOI: https://doi.org/10.1016/j.xinn.2023.100493

Robotic surgery in China

原文链接：https://www.cell.com/the-innovation/fulltext/S2666-6758(23)00127-3

DOI: https://doi.org/10.1016/j.xinn.2023.100499

2.7

Articles

Experimental quantum simulation of a topologically protected Hadamard gate via braiding Fibonacci anyons

Fluctuating magnetic droplets immersed in a sea of quantum spin liquid

Deciphering “the language of nature”: A transformer-based language model for deleterious mutations in proteins

原文链接：https://www.cell.com/the-innovation/fulltext/S2666-6758(23)00115-7

DOI: https://doi.org/10.1016/j.xinn.2023.100487

2.8

Reports

Obese Ningxiang pig-derived microbiota rewires carnitine metabolism to promote muscle fatty acid deposition in lean DLY pigs

DnaQ mediates directional spacer acquisition in the CRISPR-Cas system by a time-dependent mechanism

原文链接：https://www.cell.com/the-innovation/fulltext/S2666-6758(23)00123-6

DOI: https://doi.org/10.1016/j.xinn.2023.100495

Rational multivalency construction enables bactericidal effect amplification and dynamic biomaterial design

Progress toward the sustainable development of world cultural heritage sites facing land-cover changes

2.9

Reviews

Technologies and perspectives for achieving carbon neutrality

Gut microbiota in muscular atrophy development, progression, and treatment: New therapeutic targets and opportunities

Flexible electronics for cardiovascular healthcare monitoring

3. Brief Introduction | 期刊简介

3.1

All Disciplines of Science | 期刊的学科领域

Fig. 1 An International Journal of Science

3.2

Paper Types | 文章要求

Table 3 General Requirements

3.3

First Impact Factor | 首个影响因子

Fig. 2 Milestone

4. Why？| 为什么投稿？

4.1

Quick evaluation & peer-review (regular < 2 weeks, fast track < 3 days) | 快速审稿

4.2

Polish figure & table | 高颜值学术图表打磨

4.3

Make a cover page | 小同行/大同行/大众都能理解

4.4

Promote your article worldwide | 好文章·多宣传

4.5

Indexed by ESCI, Scopus, PubMed, et al. | 已被主流数据库收录

5. Promotion | 大力宣传文章

秉承“好文章、多宣传”的理念，编辑部一直在多渠道推广您的文章！

5.1

Most Read | 最多阅读

Fig. 3 cell.com/the-innovation (2023-09-10)

5.2

Dragon Man | “龙人”传奇

Fig. 4  > 200,000,000 Reading for Homo longi

5.3

WeChat | 官微传播力

Table 4 WeChat Promotion Top 5

5.4

XinhuaNet | 主流媒体

Fig. 5 Reported by XinhuaNet

5.5

Twitter | 推特宣传

Fig. 6 Twitter Promotion

5.6

Social Media | 社交媒体

5.6.1 WeChat | 公众号：TheInnovation创新

5.6.2 Weibo | 微博：TheInnovation创新

5.6.3 Channels | 视频号：TheInnovation创新

5.6.4 TikTok | 抖音：The_Innovation

5.6.5 LinkedIn | 领英：The Innovation

5.6.6 Instagram | 照片墙：the.innovation.journal

5.6.7 Twitter | 推特：the_innovationJ

5.6.8 Facebook | 脸书：the.innovation.journal

5.6.9 Kuaishou | 快手：Innovation创新

5.6.10 Xiaohongshu | 小红书：TheInnovation创新

5.6.11 Zhihu | 知乎：TheInnovation

5.7

Live & Webinar | 学术直播

Table 5 Live & Webinar Audience

（已有16,724,089人次观看直播）

5.8

Email Campaign | 精准Email推送

根据文章主题，将您的文章精准推送到全球范围内的小同行（1,000—5,000 emails/paper）

5.9

Virtual Collection | 虚拟专辑

小编根据文章的内容整理了13期不同主题的虚拟专辑，6期Best GA评选，向科研同行进行推介。

JAN

10

FEB

08

FEB

08

FEB

10

FEB

10

FEB

14

FEB

16

FEB

28

MAR

02

MAR

03

MAR

07

MAR

24

JAN

22

MAR

04

MAR

27

APR

03

MAY

02

MAY

27

JUL

07

6. Call for Paper | 2023年主题

Fig. 7 Topic in 2023

7. Submission | 投稿链接

Submit your manuscript via:

www.editorialmanager.com/the-innovation

Fig. 8 Submission Process

 8. 2023 Plan | 出版规划

Table 6 Issue Dates 2023

 9. Interaction | 抽奖互动

长按识别小程序即可参与抽奖

期刊简介

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The Innovation是一本由青年科学家与Cell Press于2020年共同创办的综合性英文学术期刊：向科学界展示鼓舞人心的跨学科发现，鼓励研究人员专注于科学的本质和自由探索的初心。作者来自全球55个国家；已被136个国家作者引用；每期1/5-1/3通讯作者来自海外。目前有196位编委会成员，来自21个国家；50%编委来自海外；包含1位诺贝尔奖获得者，37位各国院士；领域覆盖全部自然科学。The Innovation已被DOAJ，ADS，Scopus，PubMed，ESCI，INSPEC，EI等数据库收录。2022年影响因子为32.1，CiteScore为23.6。秉承“好文章，多宣传”理念，The Innovation在海内外各平台推广作者文章。

期刊官网：

www.the-innovation.org

www.cell.com/the-innovation

期刊投稿（Submission）：

www.editorialmanager.com/the-innovation

商务合作（Marketing）：

[e-mail]

Logo｜期刊标识

See the unseen & change the unchanged

创新是一扇门，我们探索未知；  

创新是一道光，我们脑洞大开；  

创新是一本书，我们期待惊喜；  

创新是一个“1”，我们一路同行。

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The Innovation