褚宏远课题组博士后招聘[Van Andel Institute]
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Van Andel Research Institute (VARI), a leading independent biomedical research facility, is dedicated to determining the epigenetic, genetic, molecular and cellular origins of cancer, Parkinson’s and other diseases, and translating those findings into effective therapies. The Institute is home to more than 300 scientists and support staff that work in on-site laboratories and in collaborative partnerships that span the globe.
VARI has seen immense growth in the past year, hiring over 6 new Principal Investigators to start research labs with the goal of improving health and enhancing the lives of current and future generations.
One of these new Principal Investigators,Hong-yuan Chu, Ph.D., will be joining VARI in January 2019. Dr. Chu’s research aims to study the synaptic, cellular, and circuit adaptations in the brain during disease progression using progressive mouse models of Parkinson’s disease (PD).
The Chu lab, a member of the Center for Neurodegenerative Science (https://vari.vai.org/research-groups/), is seeking an outstanding candidate for a postdoctoral researcher position.
The project is to define the synaptic, cellular, and circuit mechanisms underlying progressive degeneration of midbrain dopaminergic neurons and the associated pathological neuronal activity of basal ganglia nuclei using mouse models of PD (Chu et al, Neuron, 2015, 2017). The ultimate goal is to design novel cell-type- and circuit-specific strategies to slow disease progression and to develop therapeutic tools for devastating motor dysfunction of the disease.
To achieve this goal, the successful candidate is expected to apply brain slice and/or in vivo electrophysiology, combined optogenetic and chemogenetic approaches to interrogate and manipulate cellular and synaptic activity in the basal ganglia as progressive degeneration of midbrain dopaminergic neurons, and to link the cellular and circuit alterations to the expression of motor and non-motor symptoms of PD.
The successful candidate will have the opportunity to be trained with both traditional and state-of-the-art technologies for neuroscience research, and will work in a highly interdisciplinary environment that allows close interaction with growing PD research community at Van Andel Research Institute (VARI).
VARI provides postdoctoral training opportunities to scientists beginning their research careers (https://vari.vai.org/postdoctoral/). The fellowships are to help promising scientists advance their knowledge and research experience and at the same time support the research endeavors of VARI under the mentorship of a VARI Faculty member. All VARI Postdoctoral Fellows are encouraged to apply for external funding as soon as it is practical and reasonable after hire. Receiving a fellowship award provides recognition for both the fellow and VARI!
QUALIFICATIONS
A Ph.D. or equivalent degree, in Neuroscience, Physiology, or related field, is required.
Demonstrated proficiency as evidenced by first-author publication(s) in peer-reviewed journals and is interested in acquiring new skills.
Prior experience with patch clamp recording or in vivoextracellular recording is highly preferred.
Experience in at least one of the following skills would be favorable: rodent stereotaxic surgery, animal models of neurological disorders, immunohistochemistry procedures, rodent behavioral analysis, and virus-mediated neural circuit tracing.
Programing experience (e.g. Matlab, python) would be a plus.
DESCRIPTION OF A SUCCESSFUL CANDIDATE
A self-driven individual with genuine interest in neural circuit study using cutting edge technologies.
A highly motivated individual with excellent time management and organization skills.
A detail-oriented researcher that thinks critically to effectively design experiments and solve complex research problems.
A collaborative, hands-on researcher who proactively shares knowledge and expertise with lab members.
Excellent written and oral communication skills.
HOW TO APPLY
A cover letter describing your research interests, experience, and how you might contribute to the Chu Lab’s research.
An up-to-date Curriculum Vitae.
A list of 3 individuals who have agreed to act as references along with their contact details.
This position will be open until filled and will be reviewing applications on an ongoing basis. To apply, please email Hong-Yuan Chu, Ph.D. at hongyuan.chu@vai.org.
VARI is committed to achieving excellence through increasing diversity. We actively encourage applications from women, persons of color, persons with disabilities, and other underrepresented groups.
Van Andel Institute is an EEO and Affirmative Action Employer
About Grand Rapids, MI
Van Andel Research Institute is located in downtownGrand Rapids, MI which is the second largest city in Michigan and the largest city in West Michigan. Grand Rapids offers a remarkable combination of cosmopolitan atmosphere and small town warmth, known for its philanthropic and sustainability-driven community, and is ranked one of "America's Top 100 Places to Live."
Located on the banks of the Grand River, Grand Rapids offers all the big-city excitement you'd expect from a million-resident metropolis, featuring hundreds of restaurants and nightspots, theatres, museums, sports and concerts. The safe and clean downtown is surrounded by an eclectic mix of walk-able neighborhoods.
With a medical and life sciences industry boom, strong entrepreneurial activity, dedication to green building and living, and innovative employers, Grand Rapids' diverse economy continues to grow, offering endless career opportunities.
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