mSystems和Microbiology Spectrum杂志“肠道微生态专题”论文征稿
The following article is from 热心肠研究院 Author 热心肠小伙伴们
美国微生物学会（American Society for Microbiology，ASM）是生命科学领域中全球最大且历史最悠久的会员组织，创办了多个高影响力学术期刊。目前会员超过 30000 人，旗下杂志超过 18 本，ASM 的使命是促进及推动微生物科学发展。ASM 旗下期刊 mSystems （IF: 6.633）与 Microbiology Spectrum （IF: 5.465）在本届中国肠道大会期间专门推出肠道微生态专题，并特别展示中国学者研究论文集。mSystems 杂志主编 Jack A.Gilbert 教授也将在 5 月 30 日下午的期刊沙龙会场通过视频发言介绍杂志，欢迎致力于肠道微生态领域的专家学者踊跃投稿。
《热心肠先生》平台也将与 ASM 旗下学术期刊展开多角度合作，为中国原创研究发声，持续提升中国原创研究的国际影响力。在此特别感谢 ASM 青年中国大使陈章然博士的帮助和支持！
以下是 mSystems 与 Microbiology Spectrum 杂志的肠道微生态专题征稿信息，以及 mSystems 杂志精选的中国学者研究论文集，欢迎查阅。也可点击文末的“阅读原文”至 ASM 网站查看详情。
■ About the Special Series on the Gut
Emerging evidence highlights the importance of gut microbiota to health and disease. mSystems and Microbiology Spectrum are pleased to launch a series hightlighting basic, clinical and applied research characterizing the gut microbiome in humans and animals, exploring its role in individual health, identifying therapeutic opportunities in the context of disease, and describing potential effects of gut microbiota on an ecosystem.
Submit your research to mSystems or Microbiology Spectrum to be included in this special series.
You may submit to either journal. Your paper will undergo the normal editorial evaluation and peer review process. If accepted, your paper will be included in this special series.
■ Spotlight on China
As part of this special series on the gut, launched during the 2021 China Gut meeting, we are pleased to highlight important published work in mSystems from Chinese scientists studying the gut microbiome.
◆ mSystems | Article |
Heritable Gut Microbiome Associated with Salmonella enterica Serovar Pullorum Infection in Chickens
Jinmei Ding，Hao Zhou, Lingxiao Luo, Lu Xiao, Kaixuan Yang, Lingyu Yang, Yuming Zheng, Ke Xu, Chuan He, Chengxiao Han, Huaixi Luo, … SHOW ALL
The present study investigated the association among the host genome, the gut microbiome, and S. Pullorum infection in chickens. The results suggested that the gut microbial structure is altered in S. Pullorum-infected chickens.
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◆ mSystems | Article |
Associations of Genetic Variants Contributing to Gut Microbiota Composition in Immunoglobin A Nephropathy
Jia-Wei He, Xu-Jie Zhou, Ya-Feng Li, Yan-Na Wang, Li-Jun Liu, Su-Fang Shi, Xiao-Hong Xin, Rong-Shan Li, Mario Falchi, Ji-Cheng Lv, and Hong Zhang
The gut microbiota and host genetics are implicated in the pathogenesis of IgAN. Recent studies have confirmed that microbial compositions are heritable (microbiome quantitative trait loci [QTL]).
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◆ mSystems | Article |
Human Skin, Oral, and Gut Microbiomes Predict Chronological Age
Shi Huang, Niina Haiminen, Anna-Paola Carrieri, Rebecca Hu, Lingjing Jiang, Laxmi Parida, Baylee Russell, Celeste Allaband, … SHOW ALL
Considerable evidence suggests that the gut microbiome changes with age or even accelerates aging in adults. Whether the age-related changes in the gut microbiome are more or less prominent than those for other body sites and whether predictions can be made about a person’s age from a microbiome sample remain unknown. We therefore combined several large studies from different countries to determine which body site’s microbiome could most accurately predict age. We found that the skin was the best, on average yielding predictions within 4 years of chronological age. This study sets the stage for future research on the role of the microbiome in accelerating or decelerating the aging process and in the susceptibility for age-related diseases.
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◆ mSystems | Article |
The Gut Microbiota in Camellia Weevils Are Influenced by Plant Secondary Metabolites and Contribute to Saponin Degradation
Shouke Zhang, Jinping Shu, Huaijun Xue, Wei Zhang, Yabo Zhang, Yaning Liu, Linxin Fang, Yangdong Wang, and Haojie Wang
The gut microbiome may play an important role in insect-plant interactions mediated by plant secondary metabolites, but the microbial communities and functions of toxic plant feeders are still poorly characterized. In the present study, we provide the first metagenome of gut bacterial communities associated with a specialist weevil feeding on saponin-rich and saponin-low camellia seeds, and the results reveal the correlation between bacterial diversity and plant allelochemicals. We also used cultured microbes to establish their saponin-degradative capacity outside the insect. Our results provide new experimental context to better understand how gut microbial communities are influenced by plant secondary metabolites and how the resistance mechanisms involving microbes have evolved to deal with the chemical defenses of plants.
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◆ mSystems | Article |
Meta-analysis of 16S rRNA Microbial Data Identified Distinctive and Predictive Microbiota Dysbiosis in Colorectal Carcinoma Adjacent Tissue
Zongchao Mo, Peide Huang, Chao Yang, Sihao Xiao, Guojia Zhang, Fei Ling, and Lin Li
Turbulent fecal and tissue microbiome dysbiosis of colorectal carcinoma and adenoma has been identified, and some taxa have been proven to be carcinogenic. However, the microbiomes of surrounding adjacent tissues of colonic cancerous tissues were seldom investigated uniformly on a large scale. Here, we characterize the microbiome signatures and dysbiosis of various colonic cancer sample groups. We found a high correlation between colorectal carcinoma adjacent tissue microbiomes and their on-site counterparts. We also discovered that the microbiome dysbiosis in adjacent tissues could discriminate colorectal carcinomas from healthy controls effectively. These results extend our knowledge on the microbial profile of colorectal cancer tissues and highlight microbiota dysbiosis in the surrounding tissues. They also suggest that microbial feature variations of cancerous lesion-adjacent tissues might help to reveal the microbial etiology of colonic cancer and could ultimately be applied for diagnostic and screening purposes.
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◆ mSystems | Article |
Antibiotic Exposure Has Sex-Dependent Effects on the Gut Microbiota and Metabolism of Short-Chain Fatty Acids and Amino Acids in Mice
Hongchang Gao, Qi Shu, Jiuxia Chen, Kai Fan, Pengtao Xu, Qi Zhou, Chen Li, and Hong Zheng
Accumulating evidence shows that the gut microbiota regulates host metabolism by producing a series of metabolites, such as amino acids, bile acids, fatty acids, and others. These metabolites have a positive or negative effect on host health. Antibiotic exposure can disrupt the gut microbiota and thereby affect host metabolism and physiology. However, there are a limited number of studies addressing whether antibiotic effects on the gut microbiota and host metabolism are sex dependent. In this study, we uncovered a sex-dependent difference in antibiotic effects on the gut microbiota and metabolome in colonic contents and tissues in mice. These findings reveal that sex-dependent effects need to be considered for antibiotic use in scientific research or clinical practice. Moreover, this study will also give an important direction for future use of antibiotics to modify the gut microbiome and host metabolism in a sex-specific manner.
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◆ mSystems | Article |
Characterization of the Pig Gut Microbiome and Antibiotic Resistome in Industrialized Feedlots in China
Chunlai Wang, Peng Li, Qiulong Yan, Liping Chen, Tiantian Li, Wanjiang Zhang, He Li, Changming Chen, Xiuyan Han, Siyi Zhang, Miao Xu, … SHOW ALL
The gut microbiota is believed to be closely related to many important physical functions in the host. Comprehensive data on mammalian gut metagenomes has facilitated research on host-microbiome interaction mechanisms, but less is known about pig gut microbiome, especially the gut microbiome in industrialized feedlot pigs, compared with human microbiome. On the other hand, pig production, as an important source of food, is believed to exacerbate the antibiotic resistance in humans due to the abuse of antibiotics in pig production in various parts of the world. This study delineates an intricate picture of swine gut microbiome and antibiotic resistome in industrialized feedlots and may provide insight for the pig producing industry.
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◆ mSystems | Article |
Dynamic Changes of Gut Microbial Communities of Bumble Bee Queens through Important Life Stages
Liuhao Wang, Jie Wu, Kai Li, Ben M. Sadd, Yulong Guo, Daohua Zhuang, Zhengyi Zhang, Yanping Chen, Jay D. Evans, Jun Guo, … SHOW ALL
Bumble bee queens undergo a number of biological changes as they transition through adult emergence, mating, overwintering, foraging, and colony initiation including egg laying. Therefore, they represent an important system to understand the link between physiological, behavioral, and environmental changes and host-associated microbiota. It is plausible that the bumble bee queen gut bacteria play a role in shaping the ability of the queen to survive environmental extremes and reproduce, due to long-established coevolutionary relationships between the host and microbiome members.
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