表观遗传系列视频18 | 冷泉港 Thomas Gingeras：循环 RNA （外泌体）

去年 8 月，「表观基因组学暑期国际讲习班」于复旦大学召开。大会邀请了国内外表观基因组学顶尖的学者，为学员们分享表观基因组学的最新进展。讲习班持续 10 天，积累了大量的视频教学资源，经过漫长整理，现将视频分享如下。

今天分享第 18 期视频，感谢您的持续关注。

主讲人简介：

Thomas Gingeras, Professor, Cold Spring Harbor Laboratory.

研究方向：Thomas Gingeras and colleagues study where and how functional information is stored in genomes. These efforts help explain the biological and clinical effects of disease-causing gene mutations in humans and other organisms. Gingeras is a leader of the ENCODE (ENCyclopedia of DNA Elements) and the mouseENCODE and modENCODE (model genome ENCODE) projects of the National Institutes of Health. His research has altered our understanding of the traditional boundaries of genes, revealing that almost the entire lengths of genomes in organisms ranging from bacteria to humans can be transcribed into RNA (pervasive transcription) and that most RNA products made by a cell are not destined to be translated into proteins (noncoding, or ncRNAs). In fact, ncRNAs are proving to be involved in a variety of other important biological functions. Some have been shown to be critical components in the pre- and post-transcriptional and translational processes, as scaffolds upon which large protein complexes are assembled and as extracellular signals. The initial studies that led to these observations have been extended to cover the entire human genome.

演讲主题：Circulating RNA(exosome)

• Exosome 的概念和功能

• Exosome 内 RNA 与细胞间通信

• Exosome 内 miRNA 与肿瘤转移

• Exosome 的检测和研究策略

https://v.qq.com/txp/iframe/player.html?vid=y0540g96nrd&width=500&height=375&auto=0
▲ Circulating RNA(exosome)（2h 39min）

特别声明：本系列视频版权归复旦大学表观基因组学暑期国际讲习班组委会所有，不得用于任何商业用途。

此前已经推送了 17 期视频：

视频15 | 同济张勇：ChIP-seq 及 DNA 甲基化分析策略（附PPT）