美国新泽西招聘CAR-NK研发副总监
Position Information
Position Title:Associate Director
Reports To:Sr. Dir of R&D
Direct Reports (#/level):3-5
Major Responsibilities:
Plan and manage R&D and development activities to meet company and functional objectives
Design and execute scale-up/down NK cell manufacturing process in a closed system
Design experiment to optimize process parameters, enhance cell engineering and manufacturing capacity, apply Quality by Design principles and Design of Experiment methodologies when necessary
Develop and lead studies of media development, cell isolation, cell activation, cell expansion, formulation/fill and cryopreservation
Prepare and review tech transfer and IND filing documents
Manage internal process development activities; initiate and keep cross team and external collaborations
Represent NK immunotherapy group among cross functional groups
Qualifications
Education:
Master/Ph.D in Biology, Immunology, Bioengineering or related field
Experience:
10+ years of experience of the field of NK biology and immunotherapy.
5+ years of supervisory experience in an industry setting
4+ cell process development and manufacturing experience
Key Capabilities, Knowledge, and Skills:
In depth knowledge of immune-oncology and NK cell based cell therapy
Hands on experience with scale-up/down cell therapy process development and optimization
Experience with cell therapy automation technologies: rocking bioreactors, closed system culture vessels, cell washers, centrifugation and separation technologies. Working experience in large-scale cell manufacturing is a plus.
Experience in GMP manufacturing of Biologics and working with external partners such as CROs and CMOs; Knowledge of cell therapies, viral vectors GMP manufacturing is a plus.
Demonstrated leadership skills to manage projects in a matrix environment
Excellent verbal and written communication skills and leadership skills
IND/BLA filing experience is a plus.
Other Requirements
Location of Role: NJ, USA
Language Requirements: English and Chinese
Travel Requirements: up to 20%