上市药企招聘临床开发/药化/生物药/抗体发现VP/SVP

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1）CNS Clinical Development Head（VP/SVP level）

Location: China (Shanghai, Beijing, Guangzhou)

Key Responsibilities:

1.As a member of Leadership Team, actively contribute to the overall governance and strategy of the Therapeutic Area, including programs, people and budget.

2.Provide leadership to ensure resources, personnel, and expertise are appropriately prioritized and deployed to successfully pursue clinical development.

3.Contribute to strategic direction of all CNS disease areas through active participation at senior levels to determine global strategies for assets and disease areas.

4.Provide technical and strategic expertise to ensure consistent processes, excellence in planning and delivery of clinical plans and study protocols on time and within budget.

5.Accountable for cross-functional development and execution of high-quality clinical strategies and development programs, regarding design, trial conduct, oversight of safety monitoring and data analysis, in full compliance with regulatory agency requirements.

6.Contribute to due diligence and evaluation of new assets for development directly or through appropriate delegation.

Requirement:

1.M.D. or PHD equivalent degree required.

2.At least 10 years in pharmaceutical clinical development.

3.Neurologic disease related clinical trial experience required and clinical experience preferred.

4.Prior experience with small and large molecules for neuroscience diseases, highly preferred.

5.Demonstrated ability for strategic thinking and contingency planning.

2）VP/SVP medicinal chemistry-Shanghai

Job Description

Creates scientific-discovery innovation for the Company; Engages in innovative and independent research in different disease areas. Leads one of our Discover Chemistry Departments; Being responsible for multiple discovery programs, ensures alignment of discovery resources to achieve program goals; Seeks out and effectively coordinates multidisciplinary programs; Leads leaders.

Requirements

1.PhD in organic or medicinal chemistry or equivalent experience, and have 15+Yrs experience with managerial experience and a strong history of accomplishment, productivity, initiative and innovation. 

2.Excellent communication and critical thinking skills are required, as well as strong functional expertise in medicinal chemistry.

3.Experience with global pharmaceutical companies is a plus. 

3)VP/SVP of Biologic Drug Discovery-Shanghai

Major Responsibilities:

1. Lead biologic drug discovery efforts covering antibody generation, humanization, protein engineering, etc.

2. Evaluate drug targets and develop drug discovery and development hypothesis;

3. Evaluate & manage external biopharmaceutical drug projects for the interest of company R&D pipeline;

4. Identify CROs and appropriate technologies to execute the programs and deliver preclinical candidates;

5. Patent drafting and internal project report/summary writing.

Qualifications:

1. PhD in biology/biochemistry/pharmacology is required; industrial or academic experience in drug discovery is preferred;

2. Strong protein engineering knowledge/experience are preferred.

3. Track record delivering biologic drug candidates into clinic are preferred.

4. The ability to conceive, design, develop, refine and adapt techniques to meet new research needs;

4）VP/SVP of Antibody Drug Discovery-Shanghai

Responsibilities: 

1.Partake in research strategies and lead our Antibody Discovery Department to build and advance early therapeutic antibody discovery pipeline.

2.Partner with Discovery Biology Department, supervise cross-functional teams ( in vitro biology, in vivo biology, DMPK, and development group) to advance the antibody discovery to PCC (preclinical candidate).

3.Provide technical expertise including antibody design (monoclonal antibodies and bi-specifics, tri-specifics, fragments thereof) and lead optimization (affinity enhancement, Fc engineering for effector function and half-life etc).

Qualifications:

1.Ph.D. in molecular biology, biochemistry, immunology or related field.

2.15+ years industry antibody discovery experience in engineering antibodies and bi-specific antibodies and their optimization and development for therapeutic application.

3.Excellent organizational and communication skills demonstrated ability to perform as a leader.

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