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【Live】A Series of Webinar on Nanomaterials and Applications

KouShare 蔻享学术 2022-07-02



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Please join the webinars at the following link: koushare.com/topicIndex/i/nanomaterials-applications


A Series of Webinar on Nanomaterials ...

Speakers:Prof. Amitava Patra、Dr Mohammad Najlah

Time in Beijing: July 25, Sunday, 8:00 PM

Time in Dallas: July 24, Saturday, 7:00 AM

Sponsors:Nanomaterials MDPI、KouShare



Welcome to A Series of Webinar on Nanomaterials and Applications


We would like to invite all the Scientific Community to participate in a Series of Webinar on Nanomaterials and Applications from April to July 2021, which is sponsored by MDPI Nanomaterials and propagated by Koushare. The Webinars were scheduled at the last weekend of each month from April to July 2021 for the convenience of audiences and the speakers.   Aim and ScopeThis series of Webinars are mainly designed to offer diverse sessions that address the Theme of ‘Nanomaterials and their applications’ for the purpose of sharing new thoughts and new advances among the experts, industrialists and understudies from look into topics of Nanomaterials to share their on-going developments and applications for Better tomorrow. The scope of the webinar series is to support global research communities by empowering clusters of Professor, Scientists, Researchers, Students and Business Delegates to meet and discuss topics of Nanomaterials with frontrunners in the field. These webinars cover diverse top-ranked specialties and budding aspects of important and relatively broad subject areas including nanomaterials design and synthesis for cancer detection, drug delivery, therapeutics, sensing and safety as well as security for our better life tomorrow. The talks are aimed for public with lay languages and are open to everyone in the world!
Sincerely yours
Wei Chen, Ph.D, ProfessorDepartment of PhysicsThe University of Texas at ArlingtonArlington, Texas, USA
Special website:koushare.com/topicIndex/i/nanomaterials-application




Dr. Chen Wei



Dr. Wei Chen is a professor at the department of Physics, UT Arlington. He has been engaged in cutting-edge nanotechnology research for many years and is an internationally renowned expert in nanomedicine and cancer nanotechnology. He is well known for his inventions in cancer nano-targeted therapy and deep cancer photodynamic therapy. Currently he has published 295 papers in famous academic journals such as PNAS, Nano Letters, Signal Transduction and Targeted Therapy(Nature), Advanced Materials, Advanced Functional Materials, Materials Today Physics, presided over the compilation of 1 monograph (three volumes), and participated in the compilation of 13 monographs. His papers have been cited more than 11460 times, and his H index is 56, including one paper with 685 citations, 13 papers with more than 200 times, 28 papers with more than 100 times. He has 20 US patents granted and he has been funded with more 30 scientific research projects with a total funding of more than 9 million U.S. dollars. His early pioneering work on thermoluminescence of nanoparticles were adopted by Charles P. Poole Jr. and Frank J. Owens in their first Textbook ‘Introduction to Nanotechnology’ published in 2003. Dr. Chen's scientific research work has attracted wide attention and has been reported by the American TV program CBS. Dr. Chen received the University distinguished record of research and creative activity award in 2020.  He is one of the 35 scientists from the country to be included in the National Academy of Inventors 2020 class of Senior Members. He was elected be a Fellow of the International Association of Advanced Materials (Sweden) and a Vebleo Fellow in 2020 and a Sigma Xi full member in 2021.



01


New Possibilities of Metal Clusters for Bio-Applications 


Abstract



Atomically precise metal nanoclusters (MNCs) is an emerging area of research due to their potential applications. We will discuss about DNA-based logic gate by probing the DNA-metal base pair in the presence of suitable additive such as metal nanoclusters and metal ions. We investigated the conformation of DNA by a photoexcited energy transfer process where the Au cluster is covalently attached with AlexaFluor 488 (A488) dye tagged DNA. Blue luminescent, pepsin-templated copper nanoclusters (Cu NCs) are synthesized for an effective peroxidase mimic. The development of Cu NC-based artificial enzymes will pave the way for versatile biomedical, environmental, and clinical applications.


Brief introduction



Prof. Amitava Patra is currently Director, at the Institute of Nano Science and Technology (INST), Mohali, and a Senior Professor at the Indian Association for the Cultivation of Science. He was born in 1965 and received his Ph. D (1993) from Jadavpur University, India. Amitava pioneered the study of two-photon spectroscopy and ultrafast carrier dynamics on the contemporary topic of 2D structures, carbon dots, metal clusters, polymeric nanoparticles, and quantum dots for light-harvesting applications. We are interested to learn the mechanisms for photo-initiated processes such as exciton dynamics, ultrafast carrier dynamics, electron transfer, and energy transfer of nanomaterials for solar energy conversion. He is the author or co-author of more than 232 scientific papers, 5 book chapters, and 2 Indian patents. He was an Advisory board member of Nanoscale and Journal of Physical Chemistry and others.
Prof. Amitava Patra is amongst the world's Top 2% scientist 2020 with a global rank of 149 in Physical Chemistry (Ranking is based on C-score). Prof. Amitava Patra has been elected as a Fellow of the Optical Society of America (OSA), and the Royal Society of Chemistry (FRSC). He is a Fellow of the Indian Academy of Sciences (FASc), India, and the National Academy of Sciences (FNASc), India. He is the recipient of National Prizes for Research in Chemical Spectroscopy and Molecular Structure, MRSI-ICSC Materials Science Annual Prize, C.N.R. Rao National Prize for Chemical Research, DAE-SRC Outstanding Investigator Award, A.V. Rama Rao Foundation Prize in Chemistry, AsiaNANO 2010 Award, CRSI Bronze Medal, Ramanujan Fellowship, MRSI Medal.  His research papers have been cited more than 10550 by peers (h-index= 56).  





02


Repurposing Drugs: New Hope for Cancer Patients & Opportunities for Pharmaceutical Industry


Abstract



With more than 200 types diagnosed worldwide, cancer has been a main risk to human health and global economy. Hence, an efficient cancer therapy is urgently needed as the development of new anticancer drugs is a lengthy and costly process. Therefore, repurposing licensed drugs for cancer therapy has attracted great research interest. For example, disulfiram (DS) is a safe anti-alcoholism drug, has not only shown important toxic activity- dependent on the concentration of copper (II) (Cu+2)- against wide range of cancer cells but also entirely reversed the chemo-resistance and cross-resistance of cancer cells. However, the clinical application of disulfiram for cancer treatment is limited by its bio-instability in the bloodstream (t1/2 < 4 min). Therefore, a long-circulating nano-drug delivery system protecting DS until reaching cancer tissues is needed.


We have developed and explored a wide range of nano-based formulations to act as “shield carriers” of DS in cancer therapy. Liposomes have attracted the main interest since they may be more translational than any other nano-carriers. PEGylation of DS-loaded liposomes have successfully extended the t1/2 of DS to 75 min in vitro, whereas PEGylated PLGA nanoparticles were able to provide a longer t1/2 ( up to 120 min) than that of liposomes. In my talk, I will shed light on the current research focusing on repurposing DS and metabolites for cancer therapy. Several formulating techniques will be evaluated, and challenges for future developments will be highlighted.
The webinar will show the importance of supporting drug repositioning projects by nanotechnology to develop efficient cancer therapies. Multidisciplinary collaborations will be proposed to develop such treatments form “bench” to “bedside”.


Brief introduction



Dr Mohammad Najlah has extensive experience as a teacher, researcher, and manager. He has an excellent research profile focusing on the development of drug delivery nano-systems for enhanced bioavailability and optimised therapeutic effects. His research on polymeric conjugates was recognised from early stages by the major international body in the field of controlled release (CRS Outstanding Oral Drug Delivery Award in 2006). Mohammad is mainly interested in repurposing safe drugs and natural materials for anticancer therapy. He has published over 70 peer-reviewed publications in the field of pharmaceutical nanotechnology and supervised eight PhD students, four Post doc researchers. Mohammad is Principal Investigator on external research grants as high as $700K and a collaborator with a wide network in industry and academia. Recently, he has been awarded a total of £240K by Innovate UK and industry collaborators for implementing a scaling up technology of nano-lipids.  At ARU, he led the establishment of £3.4 million budgeted multifunctional Lab designed to deliver multidisciplinary education and conduct research for transitional science.
He also led the establishment of new undergraduate and postgraduate programmes. As a Deputy Head of School, he has extensive experience of study management, supporting research activities and identifying the individual support needs of research and ancillary staff. He is external examiner for two UK universities and served as a chair or external examiner for several PhD vivas.


Nanomaterials (ISSN 2079-4991; CODEN: NANOKO) is an international peer-reviewed open access journal published monthly online by MDPI.


Text editor:Miaomiao Su



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