重磅喜讯！默沙东九价HPV疫苗获批适用于9至45岁适龄女性接种
重磅喜讯！
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内审编码：12-2022-CN-GSL-00479
参考文献：
1. ICO/IARC HPV Information Centre. Human Papillomavirus and Related Diseases Report. China, 2021-10-22
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a.研究设计：一项汇总中国170万女性HPV感染的流行病学研究，在多个文献数据库检索2018年10月31日之前的文献，最终纳入68项研究，采用随机效应模型分析HPV感染的流行情况。
3. 李双，李明珠，丛青，杨帆，李克敏，宋坤，尹如铁，王新宇，张国楠，隋龙，刘继红，孔北华，谢幸，魏丽惠，马丁，人乳头瘤病毒疫苗临床应用中国专家共识［J］．协和医学杂志，2021,12（02）：189-201.
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5. Li R, Li Y, Radley D, et al. Safety and immunogenicity of a vaccine targeting human papillomavirus types 6, 11, 16 and 18: a randomized, double-blind, placebo-controlled trial in Chinese males and females. Vaccine. 2012;30(28):4284-4291. doi:10.1016/j.vaccine.2012.02.079
6.Hu YM,Guo M,Li CG,et al.Immunogenicity nonin -feriority study of 2 doses and 3doses of an Escherichia coliproduced HPV bivalent vaccine in girls vs.3 doses in youngwomen[J].Sci China Life Sci,2020,63:582-591
7.Van Damme P,Meijer CJLM,Kieninger D, et al.A phase Ill clinical study to comparethe immunogenicity and safety of the 9-valent and quadrivalent HPV vaccines in men[J].Vaccine,2016,34:4205-4212
8. Lei JY,Ploner A,Elstrom KM,et al.PV Vaccination and the Risk of Invasive CervicalCancer [J]. N Engl J Med,2020,383:1340-1348
9.中华预防医学会妇女保健分会. 子宫颈癌综合防控指南. 北京：人民卫生出版社. 2017
10. 子宫颈癌等人乳头瘤病毒相关疾病免疫预防专家共识.中华预防医学杂志.2019
（备注：以上内容转自默沙东中国。版权归拥有者。仅供感兴趣的个人谨慎参考）
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