脓毒症,好文推荐:
1.What is sepsis?
Sepsis is your body's overactive and extreme response to an infection. Sepsis is a life-threatening medical emergency. Without quick treatment, it can lead to tissue damage, organ failure, and even death.脓毒症是机体对感染过度的、严重的反应,是危及生命的急症。救治不及时,脓毒症会导致组织损伤、器官衰竭甚至是死亡。2.What causes sepsis?
Sepsis happens when an infection you already have triggers a chain reaction throughout your body.Bacterial infections are the most common cause, but other types of infections can also cause it.The infections are often in the lungs, stomach, kidneys, or bladder. It's possible for sepsis to begin with a small cut that gets infected or with an infection that develops after surgery. Sometimes, sepsis can occur in people who didn't even know that they had an infection.当机体存在感染且这种感染激发了一连串的全身反应的时候,就会出现脓毒症。细菌感染是最常见的病原体,但其他病原体也可导致脓毒症。感染常见部位有:肺、腹部、肾、膀胱。脓毒症也可由很小的伤口感染或手术后感染诱发。有时候,脓毒症的感染部位无法明确。3.Who is at risk for sepsis?
Anyone with an infection could get sepsis. But certain people are at higher risk:Adults 65 or older
People with chronic conditions, such as diabetes,lung disease, cancer, and kidney disease
People with weakened immune systems
Pregnant women
Children younger than one
任何感染都可发展成为脓毒症,但有些特定人群危险系数较高,如:
65岁以上
慢性病患者如糖尿病、肺病、肿瘤、肾脏疾病
免疫系统受损
孕妇
1岁以下
4.What are the symptoms of sepsis?
Sepsis can cause one or more of these symptoms:Rapid breathing and heart rate
Shortness of breath
Confusion or disorientation
Extreme pain or discomfort
Fever, shivering, or feeling very cold
Clammy or sweaty skin
It's important to get medical care right away if you think you might have sepsis or if your infection is not getting better or is getting worse.呼吸增快、心率增快
呼吸短促
意识障碍、定向力障碍
疼痛、不适
发热、寒战、畏寒
皮肤黏湿、湿冷
5.What other problems can sepsis cause?
Severe cases of sepsis can lead to septic shock, where your blood pressure drops to a dangerous level and multiple organs can fail.脓毒症重症患者可以出现脓毒症休克,此时患者血压下降至危险水平,并出现器官功能障碍。6.How is sepsis diagnosed?
Your health care provider may use many tools to make a diagnosisA medical history, which includes asking about your symptoms
A physical exam, including checking vital signs (your temperature, blood pressure, heart rate, and breathing)
Lab tests that check for signs of infection or organ damage
Imaging tests such as an x-ray or a CT scan to find the location of the infection
Many of the signs and symptoms of sepsis can also be caused by other medical conditions. This may make sepsis hard to diagnose in its early stages.病史采集,包括患者症状
体格检查,包括一些体征诸如体温、血压、心率、呼吸
实验室检查,诸如感染指标和器官功能
影像学,诸如X线和CT,这能够帮助确定感染部位
需要知道的是,脓毒症的症状和体征还可以由其他疾病引起,这会导致脓毒症诊断困难,尤其是无法早期诊断脓毒症。
7.What are the treatments for sepsis?
It is very important to get treatment right away. Treatment usually includesAntibiotics
Maintaining blood flow to organs. This may involve getting oxygen and intravenous (IV) fluids
Treating the source of the infection
If needed, medicines to increase blood pressure
In serious cases, you might need kidney dialysis or a breathing tube. Some people need surgery to remove tissue damaged by the infection.重症患者可能需要肾脏替代和呼吸支持。一些患者需要接受手术治疗,移除感染所致的损伤组织。
8.Can sepsis be prevented?
To prevent sepsis, you should try to prevent getting an infection:Take good care of any chronic health conditions that you have
Get recommended vaccines
Practice good hygiene, such as handwashing
Keep cuts clean and covered until healed
关注慢性病患者,注意其身体情况
预防接种
注意手卫生,降低院内感染发生率
保持伤口卫生
来源:NIH官网: National Institute of General Medical SciencesCenters for Disease Control and Prevention